Abstract
Total anthocyanins were extracted from six sweet cherry cultivars grown in Sakarya, Turkey. In vitro inhibition effects of the
extracted total anthocyanins on purified carbonic anhydrase I and II were investigated using CO2 as a substrate. All the extracted
total anthocyanins inhibited the activity of the human carbonic anhydrase (hCA) I and II enzymes. Among all the cultivars,
‘Karakiraz’ was found to be the most active on both hCA I (IC50 = 30.59 μg/mL) and hCA II activity (IC50 = 44.52 μg/mL).
Additionally, all the cultivars have higher inhibitory activity on hCA I than hCA II.